How would you set outgoing email to a noreply address for notifications (get too many failures) but when sending bulk mail, it sends from an active mailbox? It seems Invision can do this with a noreply@ and support@.

You'd have to edit the outgoing email in email settings every time you wanted to send a bulk mail, unless I am missing something. No place for a second one or any options in Bulk Mail. Thanks!

Anyone know?

im assuming support@ is setup through nexus/commerce for their ticket system.

No that's where newsletters come from.