So more discovery...
When viewing CSS on the borked version almost all the values for hex colors are a hash character (#). Additionally there's other code in there seems to relate to that special character:
box-shadow:0 1px 1px htmlspecialchars( '#', ENT_QUOTES | ENT_DISALLOWED, 'UTF-8', FALSE ), 0px 1px 5px htmlspecialchars( '#', ENT_QUOTES | ENT_DISALLOWED, 'UTF-8', FALSE ) inset ;
I'm guessing that the last color tweak I did, I must of hit the hash instead of the number "3" and it triggered a flaw of some sort that made me lost all of it.
I have a ticket open with IPS support but think I just uncovered a major flaw with their editor.