Has it affected me? Yes and no. Many here know I'm in that age group which is "at risk". (I'll be 65 in 2 months.)
Since I live alone and work from home, and have no one that I have to care for other than myself (and the cat), self-isolation is simply not a problem. I have about 3 weeks of food in stock if I ration it a bit, 2 weeks if I eat normal amounts. And I've switched to using Amazon Fresh for food supplies. That really does negate any need to go out.
Besides, I have no social life anyway, lol.
Will I be going anywhere I absolutely do not have to go? No. There's no sense risking exposure, even though I'm healthy for my age. Add to that the fact that my health insurance has a $6700 deductible (which I really can't afford to pay anyway). Medicare kicks in when I turn 65, so I will be taking as little risk as I possibly can for the next two months. The longer I can avoid catching it, the better are my chances of not going bankrupt from a hospitalization, and the more likely an affective treatment will be found in that time frame.
So while this has affected my life a bit, it's only a minor inconvenience, at least at this point, and I plan to just "play it safe".
I do worry about those who have kids and/or a job which requires them to commute, though.